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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Kovsies welcomes first-years into the fold
2015-01-20

Three first-year students from the Kestell residence that attended the first-year welcoming.
Photos: Johan Roux


 

Few life experiences are as exciting as becoming part of a university. On Friday 16 January 2015, Kovsies embraced our first-year students into our family after great anticipation.

That evening, first-years and their parents streamed to the Red Square on our Bloemfontein Campus where they were formally welcomed. This event also served to kick off the 2015 Gateway Programme – an orientation programme for all our first-years.

Dr Choice Makhetha, Vice-Rector: External Relations, addressed the first-years and congratulated them on their excellent matric results.

“The fact that you are here is a testimony to the level you are able to work at,” Dr Makhetha said.“You will have fun and make friends at the UFS. Your friends will be from different backgrounds and speak different languages than you. Embrace it all. You are now a part of the UFS family.

President of the Student Representative Council (SRC), Mosa Leteane, also reassured first-years that they are where they belong – at a university that inspires excellence.“This is the only space where the university’s international relations give opportunity to first-years to travel abroad with our F1 Leadership for Change Programme,” Leteane said. “It is the only space where the rector openly talks to his students, without having an appointment. It is the only space in our country where no student goes hungry due to our No Student Hungry (NSH) Programme.”

The following evening provided a spectacular live show with well-known artists Karen Zoid and Vusi Mahlasela entertaining the crowd. They performed alongside the Free State Symphony Orchestra (FSSO) that added even more dazzle to this Gateway/NSH first-years concert.

On Saturday 17 January, the new-comers had an opportunity to visit their respective faculties and get to know the staff and facilities a bit better.

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