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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Tough future if nothing changes in Africa
2015-02-20

 

The Department of Political Studies and Governance at the UFS recently hosted a workshop with the Osaka School for International Public Policy and the Southern African Centre for Collaboration in Peace and Security Studies.

The workshop, which was held on Thursday 12 February, had the theme of Perspectives on African Peace and Security. During workshop sessions, thoughts and views on peace and security were discussed for both African and South African circumstances. This was the fourth year of this joint workshop at the UFS.

Prof Hussein Solomon from the Department of Political Studies and Governance at the UFS shared some notes:

“In terms of South Africa, the fact that only 11% of South Africans have a post-school education holds negative prospects for us attaining a so-called ‘knowledge economy’”, says Prof Solomon.

“This also means that unemployment will continue to remain high since, in certain key areas, the South African economy is quite sophisticated, and needs a sophisticated labour force. Therefore, high unemployment translates into further social unrest, especially if one considers that youth unemployment is approaching 50%.”
 
Moving to broader issues in Africa, Solomon states that governance remains a challenge.

“There is a need to move away from Eurocentric forms of governance to more hybrid forms, implementing a mix of western forms of governance alongside more traditional forms.”

“Otherwise, the probability of conflict remains high as we look into the future. The possibility of water wars between African states is distinct.”

“Terrorism too will be with us for some time to come, with three terrorist attacks per day in Africa. Making matters worse, whether it is conflict over water or terrorist atrocities, is the African Union’s inability to resolve these issues. It simply does not have the capacity”, says Solomon.

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