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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Shimlas: Unbeaten Varsity Cup Champions!
2015-04-14

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    Photo: Johan Roux
    Spotlight Photo: Spektor Photography
    Photo gallery

The UFS Shimlas rugby team made history on Monday 13 April 2015 when they won their first ever Varsity Cup tournament, beating North-West University (NWU) Pukke 63-33 in the final.

Not only did Shimlas make history by winning their first-ever tournament title since the inaugural tournament in 2008, but they did not lose a single game in the 2015 Varsity Cup, thus claiming the cup in front of their home crowd at Shimla Park in Bloemfontein.

Shimlas outscored their traditional intervarsity rivals with nine tries to four. Pukke put the first points on the scoreboard with a penalty kick. The home side started off slowly in the first half. However, Shimlas’ lock, Johan van der Hoogt, did score the first try of the match followed by flyhalf and player that rocks, Niel Marais’s successful conversion kick. Yet, the men from the North-West retaliated full force for the greater part of the first half and, two tries later, had a 18-8 lead over the UFS team. 

Shortly after the first strategy break, Shimlas No.8, Niell Jordaan, crossed the try line following a driving maul, but the visitors received another penalty and succeeded with the kick at goal. The last ten minutes before half time saw Shimlas taking advantage, with the Pukke skipper being sent to the sin bin. Wing Maphutha Dolo hit a gap in NWU’s defense, and scored the try that put Shimlas in the lead again. Not long after, Marais sparked in making a play, offloading to flank Daniel Maartens to score a final try before half time, securing a 26-20 lead.

The second half had not been in play too long when the home side crossed the try line again, scoring their fifth try. Marais was again central in creating the play that saw Shimlas outside centre, Nico Lee, putting the points on the board.

NWU fought back again, scoring a pushover try from a scrum. But Shimlas would not give up the lead again, and a well-timed pass from Marais had Lee crossing the line for his second try.

More Shimlas tries piled up from Marais, Dolo, and Maartens, leaving the Potchefstroom side behind 63-25, giving them little opportunity to score again. One desperate consolation try by Pukke in the final seconds did manage to close the gap on the scoreboard, but it was not nearly enough to snatch the title from the hungry and undefeated Shimlas.

FNB Player that Rocks: Niel Marais
Shimlas point scorers:
Tries: Johan van der Hoogt, Niell Jordaan, Maphutha Dolo (2), Daniel Maartens (2), Nico Lee (2), Niel Marais
Conversions: Niel Marais (6)

 

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