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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Kovsie community pledge to advance equality and eradicate racism
2015-04-15

Photo: Johan Roux

Photo Gallery 
Speech by JC van der Merwe

On Monday 13 April 2015, the University of the Free State drew a line in history. Staff and students united in a singular vision: equality.

Since March 2015, the Institute for Reconciliation and Social Justice, together with the SRC, has launched the No-to-Racism/Yes-to-Equality Campaign across all three campuses with tremendous success. This campaign has now reached a high point at which the Kovsie community pledge their commitment to entrenching a culture of equality at the university. The first pledge ceremony took place on 13 April 2015 at the Bloemfontein Campus. Kovsies thronged to place their inked thumbprints on pledge posters in an inspirational show of solidarity.

“The key to transformation,” Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, said, “is putting yourself in the shoes of the other person.” When you look past yourself and acknowledge others’ experiences, the world starts to look different. A pledge, Prof Jansen continued, is a solemn promise – not only to stop bad behaviour, but to go forward resolutely with good behaviour. “You do not change a campus, you do not change a country, without being courageous,” Prof Jansen said.

The message from Mosa Leteane, President of the Student Representative Council (SRC), echoed the same belief. “Today,” Leteane said, “the UFS takes a bold and courageous step toward equality.” This new generation, which includes young people from all races, has started a new revolution. A generation that says no to discrimination and yes to equality. “We cannot afford to be ignorant or indifferent,” Leteane urged.

The remaining two campuses will also have an opportunity to publically pledge their support on the following days:
Qwaqwa Campus: Wednesday 15 April 2015
South Campus: Friday 17 April 2015

To enable the university to go beyond dialogues and consultation towards active decision-making, a University Assembly will be held on Tuesday 28 April 2015. The assembly will serve as a space for critical engagement among all university stakeholders to focus on issues such as symbols, policies, practices, and curriculum. Staff and students are encouraged to submit matters for discussion to JC van der Merwe (vdmjc@ufs.ac.za) before 22 April 2015.

The No-to-Racism/Yes-to-Equality Campaign is aligned with the declaration made by the UFS Council in November 2014, in which it states that “the Council of the University of the Free State believes very strongly in the human dignity, equality, and freedom of all people.”

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