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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

University Assembly focuses on symbols, policies, practices, and curricula
2015-04-30

On Tuesday 28 April 2015, the University of the Free State (UFS) held a University Assembly in the Callie Human Centre on the Bloemfontein Campus, which served as a space for critical engagement among staff and students to focus on issues such as symbols, policies, practices, and curricula.

The Assembly, attended by executive and senior management, members of the UFS Council and the President of the UFS Convocation, was also streamed live to the Qwaqwa and South Campuses.

The aim of the Assembly was to deal with above-mentioned issues as transformative strategies for creating a university culture that supports its Human and Academic Projects, as embedded in responsible citizenship, human dignity, and democratic participation.

In light of inclusivity, all staff and students were invited to table their views and submit it for discussion at the assembly, to be forwarded later as recommendations to the various decision-making structures of the UFS.

A total of 12 submissions were made at the Assembly. These submissions focused on the following issues:

• The Transformative power of sport at the UFS
• Four submissions on Language Policy – whether to include other languages or going onward to be an all English institution.
• Curriculum: Substance of what we teach
• Experiences of our first-years
• Four submissions on: Statues and symbols
• The Student Representative Council’s (SRC’s) responsibility and structure.

The UFS Management considers the above-mentioned submissions, as well as the University Assembly of 28 April 2015, as the beginning of a comprehensive process to stimulate discourse about these issues on various platforms of the university.

The discussions are in an early stage and no decisions have been taken yet. Final recommendations on the issues will be submitted to the normal decision-making structures of the university, such as the Rectorate, Senate, and Institutional Forum, after which it will ultimately be presented to the UFS Council for approval.

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