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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

New residence planned for UFS South Campus
2015-05-14

The newly-planned residence
Illustration: Typology Architects

The South Campus of the University of the Free State (UFS) in Bloemfontein has seen a great influx of students in recent years. This campus provides academic access to the UFS for deserving matriculants who do not meet the requirements for entry into mainstream degree studies through the University Preparation Programme and Extended Degree Programmes.

In addition, it also offers studies to long-distance learners. The current number of contact students – those who physically attend class at the South Campus – stands at 1 673. At the moment these students stay either on the Bloemfontein Campus or in private accommodation. This is about to change as a new residence is being built for the South Campus.

The newly-planned residence will provide two hundred and fifty beds within two main blocks – each consisting of three floors. Since the campus is located in a predominately industrial area with very few housing facilities in the area, this will fill the urgent need for accommodation.

Each floor of the residence will consist of two wings with forty beds and twenty double rooms. In addition, each floor will have separate laundry/drying and cleaners’ facility shared by both wings on that floor. Each wing will have its own ablution block, study room, communal lounge, and kitchen.

Four separate single-room flats will also be available – each sharing a lounge, kitchen, and bathroom, with a laundry facility separate from that of the main blocks.

The building project is scheduled for completion by the end of June 2016.

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