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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

New infrastructure development project planned for the Bloemfontein Campus
2015-06-03

Illustration by Incline Architects

The university community can look forward to two new infrastructure development projects on the Bloemfontein Campus. The construction of a new parking area for staff and students accommodated in the new Education Building, will begin as early as June 2015.

The project includes 113 parking places for students and 16 covered parking places for staff. According to Nico Janse van Rensburg, Senior Director at University Estates, the project will be tackled using several green approaches. “The parking area’s lighting will be solar-powered. The surface will not be the normal paving stone but will permit the water to drain into the ground and in this way be more environmentally friendly and minimise the greenhouse effect,” he says.

Several indigenous trees will beautify the area.

The new parking area will be situated opposite the UFS Sasol library’s student parking area, between the cricket field and the present parking area at the Education Building.

The second project involves a new roof structure at the Bloemfontein Campus’s main entrance security gate.

Since August last year, the university has been enforcing rigorous entrance controls. No person can access any of the five entrances of the Bloemfontein Campus without a valid entrance card. Should individuals not have a card, they must access the campus at Gate 5 in DF Malherbe Avenue where a temporary access card will be issued to them.  Scanning for visitors and service providers is also available at Gate 1 (Nelson Mandela Drive) and Gate 5 (DF Malherbe Avenue).

The  roof structure at the main entrance will serve as a security point. Primarily, it will provide shelter from the elements for those staff manning the area.

Nico says that the plan is to complete the projects before the end of the year. The projects are currently in the planning phase.

“The gate may possibly be closed for a day or two but the main work will be done during weekends. Certain lanes may also be closed from time to time to ensure the safety of both users and construction workers,” says Nico.

Staff and students will be advised well in advance if and when the gate will be closed.

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