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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Consumer Science at the UFS awards three PhDs
2015-07-08

Dr Gloria Seiphetlheng, Dr Natasha Cronje, Dr Ismari van der Merwe and Prof Hester Steyn.
Photo: Leonie Bolleurs

For the first time in its history, the Department of Consumer Science in the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) earned three doctorates at one graduation ceremony this year. This week three PhDs were awarded to Ismari van der Merwe, Natasha Cronje, and Gloria Seiphetlheng at the Winter Graduation that took place on the Bloemfontein Campus.

Electrochemically-activated water is widely used in the food and other industries, due to its excellent environment-friendly properties. However, it is not used in the textile industry yet, because too little research has been done to determine the possible positive and negative impact it may have on textiles.

With the thesis, The evaluation of catholyte treatment on the colour and tensile properties of dyed cotton, polyester and polyamide 6,6 fabrics,  Dr Cronje, a lecturer in the UFS’s Department of Consumer Science, and Dr Seiphetlheng from the Serowe College of Education in Botswana,  provided major new information with the thesis, Anolyte as an alternative bleach for cotton fabrics. This information is essential when considering the application of catholytes and anolytes in the textile industry.

Electrochemically-activated water divides water in catholytes and anolytes. The anolyte part is used as a disinfectant and bleach. It is not really suitable for domestic use, as it can cause colour loss in coloured textile products. However, it can be used in the hospitality industry where white sheets, towels, etc., are used and washed on a regular basis.

The catholyte part of the water has properties similar to washing powder. It can also be used in the textile industry as washing liquid.

According to Prof Hester Steyn, Head of the Department of Consumer Science and supervisor of all three PhD candidates, this electrochemically-activated water is also very eco-friendly. “It has a short shelf life. If the electrochemically-activated water isn’t utilised, it returns to normal water that wouldn’t harm the environment. No water is therefore lost, and no waste products are released that would contaminate the environment,” she says.

Dr Van der Merwe’s research focused on Degumming Gonometa postica cocoons using environmentally conscious methods. A lecturer in the Department of Consumer Science, she demonstrated that simple and environmentally-friendly methods can be used with great success to procure wild silk from the cocoons of the Gonometa postica worms living in the camel thorn trees found in the Northern Cape and Namibia.

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