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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Colloquium probes solutions for student hunger
2015-08-03

While higher education is deemed necessary for future financial security, high tuition and accommodation fees, as well as increasing food prices, are forcing students to drop out of university.

Dr Louise van den Berg, Senior Lecturer and Researcher at the University of the Free State (UFS), says university campuses are not often associated with food insecurity, but, due to the increase in first-generation students and students of low-income households receiving tertiary education, student hunger at some of the country’s prominent campuses needs urgent intervention.

On 14 August 2015, the University of the Free State (UFS) will host the first higher education colloquium in the country, on food insecurity on university campuses.  Best practices will be shared, exploring the available research on student food insecurity at institutions of higher education. Programme of the colloquium.

A study by the UFS Department of Nutrition and Dietetics found that as many as 60% of students on our campuses were food-insecure, and experienced hunger. This study was the first of its kind in South Africa, and led to the No Student Hungry Bursary Programme (NSH) at the UFS. The level of severe food insecurity reported was much higher than that reported in Australia, New York, and Hawaii by the only other three studies that have been done.

“The UFS is not the only campus struggling with food insecurity,” say Dr Van den Bergh.

“The general misconception is that a student, having money for studies, should have money for food. Funders need to reassess bursaries, keeping issues such as food insecurity in mind, and not just focusing on tuition.”

Bursaries, especially government funding, became easily available to bridge the inequality gap in our country.

“Although bursaries pay for tuition, many students have no resources for food. Universities currently have a 50% drop-out rate currently, with many students dropping out due to poverty.”

 

What is NSH?

 

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