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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Universal Access and Universal Design approach align UFS with international standards
2015-08-11

Making mobility for students with disabilities easier, First Car Rental representatives hand over the brand new Toyota Quantum to Hestie Veitch, Head of CUADS.
Photo: Valentino Ndaba

The Centre for Universal Access and Disability Support (CUADS) launched successfully on 24 July 2015. The objective was “to make more people on campus and from the greater UFS community aware of the services that we provide, and to spread the word about Universal Access.”

“Since the center was founded in 2001, structural and systematic developments have occurred in order to create a welcoming and accessible learning environment that grants students opportunities to be successful in their academic endeavours. Thus, the Unit for Students with Disabilities (USD) has evolved into the CUADS in support of the social model of disability,” said Hetsie Veitch, former Head of the Centre.

Implementing the Universal Access and Universal Design approach has aligned the University of the Free State (UFS) with international standards.

Mingling with the experts

Vendors from across the country displayed their products, and offered demonstrations of functional gadgets and essentials at the event.

Marita Erlank from Sensory Solutions demonstrated how to operate the specialised scanner, which converts printed material to enlarged electronic text and audio, using the Open Book software.

Representing the university’s Sign Language Student Association were Carla Bester, Elrie de Toit and Tebogo Chabangu. To support Deaf Awareness Month (September), theyplan to dedicate a weekto facilitating free workshops for students not registered for the module.

David Greenland and his teamwere also present as part of a Wheelchair Appreciation Month campaign. On 1 September2015,the group of students will raise awareness of the daily challenges faced by mobility-impaired persons by spending the day in wheelchairs.

The day ended on a festive note, by courtesy of the First Car Hire Rental Company. A brand-new Toyota Quantum was handed over as a long-term rental, enabling students of the university to travel between campuses free of charge.

CUADS aims to continue transforming the UFS into a universally-accessible environment by collaborating with internal and external stakeholders. The launch marks a significant step towards Universal Access and Design.

 

 

 

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