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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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Out of the ordinary lunch with Prof Jansen
2015-08-17

Prof Jansen and the twins pose for pictures after enjoying a laugh and chat at the lunch event.

Numerous sets of twins and a set of triplets were entertained by, and enjoyed lunch with, the Vice-Chancellor and Rector of the university, Prof Jonathan Jansen.  Wednesday 12 August 2015 marked an extraordinary day in the Kovsie history book.

The Reitz Hall in the Centenary complex was filled with echoes of laughter as Prof Jansen told “twin jokes” he had Googled earlier for the occasion. Save for the humour, he said that twins and triplets represent a unique bond.  “After all, we should be striving for a way of being together,” he said, speaking about the quest for national solidarity.

Sitting in groups of six, and after the introductions, the duos and trio were soon engaged in conversation.

Anita and Mikita Miza, who were sharing a table with Marike and Ilna Marais, told stories from their childhood.

“We did not realise that we were twins until we were in grade one,” said Anita, who is studying the same course as her sister. Mikita is in the second year of her BSoc Science degree, while her twin is a year ahead. She had to remain in Mtata, their hometown, for a year while Anita began her first year. “It was the longest year of my life,” said Mikita.

Marike and Ilna are first years in Physiotherapy and Optometry, respectively. When asked by Prof Jansen what they never share, the non-identical twins were quick to reply: “clothes,” although they still share a room. When they were in high school, fellow learners struggled to believe that Marike and Ilna are twins, because of their distinctly different looks.

The lunch united strangers, who have a unique common bond, and acted as a platform to tell interesting stories that are seldom heard.

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