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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Rag spreads the spirit of Ubuntu in Dinaweng informal settlement
2015-08-25

 

The Rag Committee teamed up with Prowess to create the first pop-up Street Store in Bloemfontein, as part of the Ubuntu Community Store Project. On 22 August 2015, the residents of Dinaweng had the opportunity to get hold of new and second-hand clothing free of charge. Soup and bread were also served to the children and the elders of the area, which is all too familiar to the media for its high unemployment, crime, and prostitution rates.

How do clothes represent Ubuntu?

From Tubatsi Moloi’s perspective, this is the team’s way of demonstrating that Ubuntu does not exist merely as a philosophy. The Rag Committee shows compassion to communities that lack resources essential to leading a dignified life.

“Ubuntu basically means uniting with the community by giving back and also thinking for those who are in need,” says the RAG Committee Executive.

Prowess, a Non-Profit Organisation (NPO) run by Kovsie students, initiated the concept which targets homeless and needy individuals unable to purchase clothing. Students from all 26 Kovsie residences and personnel have since supported the initiative by donating to the inaugural Street Store through representatives of Rag in residences.

The Street Store will continue to empower impoverished communities within the Mangaung Metro, and champion these human projects in collaboration with external stakeholders.
“We will also be working with Twee-Toring Church, although it has not yet been confirmed when we will pay them a visit,” said Tubatsi.

Providing basic needs such as clothing has the power to reinstate the dignity of people. Rag and Prowess have taken it upon themselves to practice the ideals of Ubuntu in an attempt to ensure that the less fortunate lead dignified lives.

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