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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Afrikaans Language Day invites greater university community to celebrate the language
2015-08-26

On 14 August 2015, the Vuur en Vlam Committee hosted an event which provided the university community the opportunity to celebrate Afrikaans Language Day. The occasion celebrated the establishment of the language in South Africa. With the unexpected arrival of the Dutch in 1652, the language transition proved a struggle for the indigenous peoples domiciled on African soil.

The committee’s primary objective was to change existing cultural connotations associated with the Afrikaans language.  The use of diversity can help undermine the African stereotype held about the Afrikaans language, and thus bring about a mindset shift. It is important to remember that not all Afrikaans speakers are white, and emphasis is rarely directed to the diversity of Afrikaans speakers.

Approaching the celebration, a sensitive discussion around the Afrikaans language was hosted, in which various panel members discussed the state and current outlook of the language. Prof André Keet, Director of the Institute for Reconciliation and Social Justice, who was part of the panel said, “No language gets to be misused to maintain the privilege of the past.” Director of the Free State Arts Festival, Ricardo Peach, shared the notion that “We must build on what we have, and not break it down,” while he describes himself as a “polluted language boer”. While there is a strongly-expressed hatred for the Afrikaans language, Peach maintained further that there is much work to be done in order to “Break down the link between the language and the Holocaust which took place in the homes of Afrikaans people.”

Lindiwe Kumalo, chairperson of the Vuur en Vlam Committee, said: “We are creating an awareness around campus that Afrikaans is not dead. Once you know the language, you can interact with other people, and there is no longer that language barrier.” Amongst other things, the event encouraged dialogue by creating fun and interactive activities which exposed visitors to the language.

The Vuur en Vlam Committee is committed to creating an awareness of, and vibrancy around, the Afrikaans language, and to engaging the broader university community.

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