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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Researchers reach out across continents in giraffe research
2015-09-18

Dr Francois Deacon and Prof Fred Bercovitch
busy with field work.

Researcher Dr Francois Deacon from the Department of Animal, Wildlife, and Grassland Sciences at the University of the Free State is conducting research with renowned wildlife scientist, Prof Fred Bercovitch, from the Center for International Collaboration and Advanced Studies in Primatology, Kyoto University Primate Research Institute in Japan.

Dr Deacon’s ground-breaking research has attracted international media attention. Together with Prof Nico Smit, he equipped giraffes with GPS collars, and conducted research based on this initiative. “Satellite tracking is proving to be extremely valuable in the wildlife environment. The unit is based on a mobile global two-way communication platform, utilising two-way data satellite communication, complete with GPS systems.”

Prof Bercovitch was involved with GPS tracking from elephants to koala bears.

Some of the highlights of the joint research on giraffes by Dr Deacon and Prof Bercovitch focus on:
 
• How much time do certain giraffes spend with, and away from, one another
• How do the home ranges of herds and individual giraffe overlap
• Do genetically-related animals spend more time together than non-genetically-related animals
• How much time do the young bulls, adult bulls, and dominant bulls spend with cow herds
• Herd interactions and social behaviours of giraffe
• The role of the veld and diet on animal behaviour and distribution

 

Their research article, “Gazing at a giraffe gyroscope: Where are we going?”, which was published in the African Journal of Ecology, assesses recent research by exploring five primary questions:

- How many (sub) species of giraffe exist?
- What are the dynamics of giraffe herds?
- How do giraffe communicate?
- What is the role of sexual selection in giraffe reproduction?
- How many giraffe reside in Africa?

They conclude this article by emphasising that the most essential issue is to develop conservation management plans that will save a wonderful species from extinction, and which will also enable scientists to conduct additional research aimed at answering their five questions.

In addition, they are working together on a grand proposal to get National Geographic to cover their work.

 

 

 

 

 

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