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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Deaf Awareness Month empowers the hearing impaired
2015-09-21

There are more sign languages in the world than spoken languages. About 600 000 deaf South Africans have the South African Sign Language (SASL) as their first language. There are about 40 schools for the deaf in South Africa. 90% of all deaf children are born to hearing parents. Only about 30% of speech is visible on the lips.

How many of these fundamental facts did you know?

Deaf Awareness Month serves to educate hearing communities about issues that the deaf population face on a daily basis, as well as to honour the history and culture of people who are deaf or hard-of-hearing. For the past 70 years, the University of the Free State (UFS) has dedicated September to hosting events around the topic of hearing impairment.

The theme of ‘With South African Sign Language rights, our children can!’

This year’s theme had learners from Bartimea School for the Deaf and Blind, hearing impaired UFS students, and Prof Jonathan Jansen engaged in a conversation around empowerment at a picnic held on Monday 7 September 2015 at the Red Square on the Bloemfontein Campus.

Through a sign language interpreter, Matshela, a grade 12 learner, explained that he felt empowered by the efforts the university has made to embrace and empower individuals with disabilities. He then revealed his intentions of pursuing Information Technology or Social Work studies at Kovsies.

Clifford Machete, a first-year Administration student at the university, stated how sign language interpreters gave him an ‘I can’ attitude when he first arrived at university.  “As a deaf person, I see that I am able to learn with the help of sign language interpreters. There is accessibility at the university, and I am so proud to be a student here and part of Deaf Awareness Month.”

Susan Lombaard, Lecturer and Acting Chairperson at the Department of South African Sign Language, believes that Deaf Awareness Month is about promoting human dignity.

“We want to show the world that deaf people can do everything, and that their language is as strong and important as any spoken language.”

For more information regarding Deaf Awareness Month activities, contact the South African Sign Language Department on 051 401 2251.

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