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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Professor awarded by Cardiff University for exceptional teaching and research record
2015-10-20

Prof Pieter Duvenage
Cardiff University is one of the best research universities in the United Kingdom (UK) and the world. In 2014, Cardiff was ranked number 2 and 5 among UK universities in the Research Excellence Framework for impact and quality, respectively.

Annually, Cardiff selects and recruits the most outstanding teachers and researchers from across the globe. This year, this institution bestowed on Professor Pieter Duvenage the title of Honorary Professorship in Political Philosophy for his contribution and commitment to philosophical research in South Africa and internationally. Prof Duvenage is Head of the Department of Philosophy at the University of the Free State (UFS).

Prof Duvenage has authored and co-authored four books, publishing almost 40 accredited articles in journals and books. As a distinguished scholar, he displays immense dedication to the investigation of the political implications of intellectual traditions.

Since 1997, Prof Duvenage has been lecturing philosophy as an associate professor, full professor, or visiting professor at various South African and Australian universities. He was appointed as Head of the Department of Philosophy in 2011, where he continues to explore his interests in Phenomenology, Critical Theory, and South African Intellectual History.

His rich academic history had earned him the prestigious five-year Honorary Professorship at Cardiff’s Department of Politics.  In 2014, the same university invited Prof Duvenage to be a Professorial Fellow of the Collingwood and British Idealism Centre for an indefinite period.

Professor David Boucher, Director of the Collingwood and British Idealism Centre, has played a crucial role in initiating both processes. According to Prof Duvenage, “Professor Boucher is a respected British academic and a Distinguished Visiting Professor at the University of Johannesburg.”

When Boucher announced the good news, Prof Duvenage was very surprised. “The appointment came as a total surprise. I never studied there [at Cardiff University], therefore it was purely through academic networks.”

Considering Cardiff’s reputation and Prof Duvenage’s exceptional skill sets and values, his relationship with the world-leading university in research is bound to blossom.

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