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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

UFS celebrates research excellence
2016-02-25

Description: UFS celebrates research excellence Tags: UFS celebrates research excellence

Researchers at the university were acknowledged for their new research ratings. From the left are: Prof Johann de Wet, Department of Communication Sciences; Prof Naomi Morgan, Department of Afrikaans and Dutch, German and French; Prof Corli Witthuhn, Vice-Rector: Research; Prof André Pelser, Department of Sociology; Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology; and Prof Riaz Seedat, Department Otorhinolaryngology.

During a recent gala occasion, the University of the Free State (UFS) acknowledged 15 of its researchers who received new ratings from the National Research Foundation (NRF).

According to Prof Corli Witthuhn, Vice-Rector: Research at the UFS, 37 applications have already been received for the next round of ratings by the NRF. In recent years, the university has experienced an increase in the rating of its researchers as the result of raised academic standards. These are in line with the Academic Project of the UFS. The UFS has 125 rated researchers in total.

The 15 recipients of new ratings from the NRF in 2015,are:

- Dr Tanya Beelders, Computer Science: Y2
- Dr Andrew Cohen, History: Y1
- Prof Pieter de Villiers, Theology: C2
- Prof Johann de Wet, Communication: C3
- Dr Angelinus Franke, Agriculture: C2
- Prof Jonathan Jansen, Education: B1
- Prof Riaan Luyt, Chemistry: B3
- Prof Naomi Morgan, Linguistics: C2
- Dr Trudi O’Neill, Microbiology: C1
- Prof André Pelser, Sociology: C3
- Dr Johann Rossouw, Philosophy: C2
- Prof Riaz Seedat, Health: C3
- Dr Jakub Urbaniak, Theology: Y2
- Dr Martin van Zyl, Mathematics: C3
- Prof Sue Walker, Soil, Crop and Climate Sciences: C1

The UFS also celebrated its five SARChI research chairs during this event. The main goal of the research chairs is to promote research excellence.

The five research chairs at the UFS are all established at Tier 1. Research chairs in the Tier 1 category are based on the researcher's research track record, as well as on the training record of his/her postgraduate and postdoctoral students.  Tier 1 research chairs are awarded to established researchers who are leaders in their field, and whose work is recognised internationally.

The following research chairs have been awarded to the UFS since 2013:

- Solid State Luminescent and Advanced Materials, Prof Hendrik Swart in the Department of Physics (2013-2017)
- Disease Resistance and Quality in Field Crops, Prof Maryke Labuschagne (2016-2020)
- Higher Education and Human Development, Prof Melanie Walker (2013-2017)
- Vector-Borne and Zoonotic Pathogens, Prof Felicity Burt (2016-2020)
- Humanities without Borders: Trauma, History and Memory (2016-2020) 

 

 

 

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