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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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Students have a responsibility in SA, says Ntuli
2016-02-19

Description: 2016 SRC presidents Tags: 2016 SRC presidents

Lindokuhle Ntuli (left), President of the Student Representative Council (SRC) on the Bloemfontein Campus of the University of the Free State (UFS), and Paseka Sikhosana, president of the SRC on the Qwaqwa Campus, are in agreement about their vision for the UFS in 2016.
Photo: Johan Roux

You and I have a role to play in building the new South Africa built upon the Constitution of 1996.

These are the words of Lindokuhle Ntuli, President of the Student Representative Council (SRC) on the Bloemfontein Campus of the University of the Free State (UFS). They echo his and the SRC’s message of a “campus for all students, locally and internationally, irrespective of colour.”

Ntuli and Paseka Sikhosana, president of the SRC on the Qwaqwa Campus, were in agreement about their vision for the UFS in 2016.

According to Sikhosana, a well-known slogan accentuates a feeling of uniqueness at the university. “United in diversity. No wonder we say only a Kovsie knows a feeling,” he says.

“As the SRC, we believe that complete transformation on campus is through promoting a non-sexist, non-racial, but democratic student society that acknowledges diversity and change. That further promotes and embraces one student’s difference in terms of culture, tradition, religion, and sexual orientation.”

A new South Africa

Ntuli means students have a responsibility. He referred to a quotation from Frantz Fanon’s book, The Wretched of the Earth, to illustrate this. Fanon was a revolutionary and writer whose works are influential in post-colonial studies. “Every generation has a mission. It is the responsibility of every generation to discover its mission. Once you have discovered it, you have to fulfil it or betray it into relative obscurity,” Ntuli quoted.

According to him, the South African Constitution holds pious promises of a better life for all, and each citizen needs to help to achieve that.

SRC has open door policy 

Ntuli says the UFS remains committed to human embrace, diversity, integration, and human togetherness. He added that the SRC has an open door policy, and will avail itself in helping students.

According to Sikhosana, it is the objective of the SRC to represent the student community in all interactions within the university and externally.

“There is nothing for us, about us, without us students,” he says.

• The above excerpts have been taken from Ntuli and Sikhosana’s respective welcoming speeches to first-year students on the Bloemfontein and Qwaqwa Campuses.

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