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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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Horse-riding therapy improves self-confidence in children
2016-05-10


This group of Honours students in Psychology at the University of the Free State was honoured with the best postgraduate Service Learning award at the prize-giving function of the Faculty of the Humanities. From the left are Adriana de Vries, Hershel Meyerowitz, Simoné le Roux, Wijbren Nell, Melissa Taljaard, and Gerán Lordan. Photo: Marizanne Cloete.

Horse-riding therapy helps to improve self-confidence in children, and changes their perception of themselves. It puts them in a totally new environment where they can be free of any judgement.

According to Wijbren Nell, who achieved his Honours degree in Psychology at the University of the Free State (UFS), this is the ideal therapy when working with children with disabilities. He said it was amazing to see how they developed.

He was part of a group of Honours students in Psychology who received the best postgraduate Service Learning award in the Faculty of the Humanities for their community project. In 2015, this project by Wijbren, Hershel Meyerowitz, Gerán Lordan, Melissa Taljaard, Simoné le Roux, and Adriana de Vries, was part of their module Community and Social Psychology. They were honoured at the Faculty’s prize-giving function on 15 April 2016.

Purpose of project

“Our purpose with the project was to demonstrate to the children that they could still accomplish something, despite their disabilities,” Wijbren said. The students work on a weekly basis with learners from the foundation phase of the Lettie Fouché School in Bloemfontein. Marie Olivier’s Equistria Therapeutic Development Trust serves as the site for the community project. She has a long standing partnership with the UFS.

Horse-riding and therapy

According to Wijbren, the idea was to stimulate the psychomotor functioning of the children, as well as to promote their psychological well-being. He said research has shown that there is incredible therapeutic value in horse-riding. In this specific case, it has improved the children’s self-confidence, as they may have a poor self-image as a result of their disabilities.

“At the beginning of the year, there was a girl who didn’t even want to come close to a horse, let alone getting onto the horse. We kept on trying, and, once she was on the horse, we couldn’t get her down. This was the amazing thing about the project,” said Wijbren.

Award a surprise

Wijbren said the award was a honour and surprise to his group. He was full of praise for Dr Pravani Naidoo, a lecturer in Psychology at the UFS, who coordinates the therapeutic horse riding project. “She has a tremendous passion for this project, and challenged us to think on our feet. She is a real inspiration.”

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