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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

KovsieFit caters for all
2016-05-30


KovsieFit offers a new service to students and staff for keeping fit. Photo: Charl Devenish

Students on the Bloemfontein Campus of the University of the Free State (UFS) can now work in a gym session between classes, and staff can do the same before or after work.

This is due to KovsieFit, a commercial gymnasium, which will be taking in its first members on 30 May 2016. The gym is located in the Callie Human Centre and is a project which has been a long-time dream for the UFS.

UFS boasts three gymnasiums

For the last couple of months, a lot of hard work went on behind the scenes. Kobus Calldo, conditioning coach at KovsieSport, says everybody involved with the process is happy that KovsieFit is a reality. According to him KovsieFit “is looking good and everybody involved is very satisfied” with the final product.

KovsieFit will be open Mondays to Fridays from 05:30 to 19:30, and on Saturdays from 07:00 to 11:00. Prospective members will have to undergo health screenings before they may join. KovsieFit also has lockers available. The gym will be managed by a committee.

The High Performance Centre of the UFS, where athletes and sports teams are training, is located next to KovsieFit. At the beginning of the year, KovsieSport’s offices also moved to the Callie Human Centre. A third gymnasium, the Sports Science Centre – the former Biokinetics gymnasium – is located next to the Mabaleng Building. This will mainly be used as a rehabilitation centre.

Service to university community

According to Calldo KovsieFit caters for all and offers the same service to its members as any other commercial gymnasium. The target mark is primarily students and staff, and then the rest of the city.

“It is cheaper and conveniently close to the residences for students on campus. Staff members can have a gym session during lunch or before or after work.”

Wide variety of exercises

“We offer spinning, pilates, aerobic, zumba, and all those type of classes too. We will start with four classes a day until business picks up,” Calldo says.

KovsieFit also offers aerobic apparatus such as treadmills, rowers, and electric bicycles. A gymnasium circuit, two Olympic platforms, and different types of weights and machines are also available.

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