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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

UFS community makes difference through Big Give Project
2016-06-10



Food for the needy. From left is Annelize Visagie, Health and Wellness;
Vicky Simpson, No Student Hungry Food Bursary Programme;
Elizabeth Msadu, Health and Wellness; and Lorinda Slippers, Student
Representative Council Rag Community Service, at the handover of
the food and cash collected by the RAG Big Give Project.
Photo: Jóhann Thormählen

Thanks to the caring community of the University of the Free State (UFS), students in need were provided for during exams, and will receive more food in the cold winter months.

Once again, staff and students made valuable contributions at the successful RAG Big Give Project, where food contributions of R 38 176.20 and cash donations of R25 000 were received. Staff, residences, and the RAG Committee made these donations as part of the project on 5 May 2016, when contributions were made at the Bloemfontein Campus gates of the UFS. An extra donation by Imperium, a residence on the Bloemfontein Campus, of R20 000 for FutureLife helped to achieve the grand total of food contributions.

According to Vicky Simpson, Assistant Officer at the No Student Hungry Food Bursary Programme (NSH), the food donation is for a designated group of students who have already been identified as food insecure by the social work office. “It will be distributed to them on a monthly basis,” she said.

The handover of food collected was done on 25 May 2016 at the RAG Food store by the RAG Office to Health and Wellness and the NSH. The RAG Office thanked the UFS community for its contributions to the project. Parexel, who made cash and food donations, received special mention. Simpson said “the food will make a huge difference in the lives of students who do not know where their next meal will come from”.

According to Jaco Faul, Senior Assistant Officer Rag CS, his office is already looking forward to the next instalment of the Big Give Project. “We challenge faculties and staff members for the forthcoming Rag Big Give project in October to see if we can beat the amount collected this time.”

 

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