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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Free State Arts Festival and the Department of Afrikaans and Dutch, German and French (UFS) launches first crossword tournament in SA
2016-06-14

History will be made at the Free State Arts Festival, which will this year be held in Bloemfontein from 11 to 16 July. For the first time ever in South Africa, a Crossword Tournament will be presented for the public, where Afrikaans word and language lovers can test their knowledge and speed against other competitors.

With the help of the Department of Afrikaans and Dutch, German and French, as well as Xword, the RSG Crossword Tournament will be presented on the university’s campus. In several knockout rounds on Friday 15 July, contestants will have to complete three different types of crosswords compiled by the experienced crossword team at XWord.  Points will be awarded according to a formula measuring accuracy and speed. The top ten contestants will go through to a semi-final on Saturday 16 July, after which three finalists will be selected to compete against each other in the Grand Finale. 

Apart from the coveted title, DIE RSG BLOKRAAIKAMPIOEN, prizes which are up for grabs include a year’s access to the news platforms of Netwerk24 for all three finalists, a variety of dictionaries from Pharos and Longman-HAT, a wide range of crossword books published by LAPA, and many more.

Interested persons can find more information about the RSG Crossword Tournament at www.xword.co.za. Links are also provided to free crosswords which can be printed to practice ahead of the tournament. Interested people are requested to send their names, cellphone numbers, and Email addresses to Albe Grobbelaar at XWord in advance in order to facilitate the planning for the expected number of participants. The address is albegrobbelaar@gmail.com

The cost for participants is R50, which is payable on the day of the elimination rounds at the venue on campus, South Block 1. The entrance fee includes a copy of XWord’s popular book, AfriBlokkies Blokkiesraaisels.

(Further inquiries: Albe Grobbelaar – 082 447 1900)

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