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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

UFS finances are fundamentally sound
2007-12-01

The finances of the University of the Free State (UFS) remain fundamentally sound and a higher than expected surplus of about R26 million was achieved in the 2007 budget.

This announcement was made last week during the last meeting of the UFS Council by Prof. Frederick Fourie, Rector and Vice-Chancellor.

“Up to now, we could finance the considerable investments in the infrastructure from discretionary funds, in spite of the fact that Council granted us permission during 2005/06 to take up a loan of R50 million for this purpose,” said Prof. Fourie.

The higher than expected surplus of about R26 million will be used among other things for the financing of infrastructure in order to further postpone the taking up of a loan.

In support of the drive to reposition the UFS nationally as a university that is successfully integrating excellence and diversity, R5 million will be made available from the surplus for this purpose.

The Council also approved the following allocations for 2008 for the key strategic pillars of a good practice budget for the university:

Information sources: R21,1 million
IT infrastructure: R3,5 million
Replacing expensive equipment: R7,05 million
Research: R18,1 million
Capital expenditure: R28,2 million
Maintenance capital assets: R18,2 million
Reserves: R6,3 million
Personal computers for the computer laboratory: R3,5 million

For the Qwaqwa Campus R2,5 million has been set aside for these issues.

In terms of strategic priorities R8 million was allocated for the academic clusters, R2 million for equitability, diversity and redress and R6 million for equity.

The projected income for 2008 will be R849 million, while the projected expenditure, excluding transfers, will be R694 million.

“Council further approved that discretionary strategic funds be largely voted to the further upgrading of the physical infrastructure, especially the Chemistry Building, the computer laboratory building, examination venues and the Joolkol,” said Prof. Fourie.

According to Prof. Fourie, funds have been reserved for the development of the academic clusters, as well as the continuation and acceleration of the transformation programme of the UFS.

“We have also managed to revise the conditions of employment of contract appointments and align it with the latest labour practices. The phasing in of the fringe benefits of this specific group of staff members will commence in 2008,” said Prof. Fourie.

Given the dependence of the income of the UFS on student numbers, a task team was formed last year to investigate the continued financial sustainability of the UFS. The core of this task team’s recommendations is:

to increase the third income stream by using the academic clusters as the main strategy; and to apply strategies such as the recruitment and extension of the postgraduate and foreign student corps, increase the income from donations and fundraising, etc.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
30 November 2007
 

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