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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Reflection should stimulate action – Prof Petersen
2017-05-25

 Description: Panel discussion: Reflection should stimulate action  Tags: Panel discussion: Reflection should stimulate action

Panellists at a discussion held by the Institute for
Reconciliation and Social Justice were, from the left,
Prof Elelwani Ramugondo of the University of Cape Town,
Prof Melissa Steyn from Wits, Prof Francis Petersen,
Vice-Chancellor and Rector of the UFS, and SK Luwaca,
president of the Student Representative Council on the
Bloemfontein Campus.
Photo: Johan Roux

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The University of the Free State (UFS) should be a place of belonging, a place where staff, academics and students belong and can make a contribution to a democratic society.

This is according to Prof Francis Petersen, Vice-Chancellor and Rector of the UFS. He was one of four panellists at a discussion, titled Diversity, inclusivity and social justice and the renewed call for decolonisation, hosted by the Institute for Reconciliation and Social Justice (IRSJ). Prof Elelwani Ramugondo from the University of Cape Town, Prof Melissa Steyn from Wits, and SK Luwaca, president of the Student Representative Council on the Bloemfontein Campus, were the other panellists.

The IRSJ facilitated the discussion, which formed part of the inauguration proceedings for Prof Petersen as new Vice-Chancellor and Rector, in the Albert Wessels Auditorium on the Bloemfontein Campus on 18 May 2017.

Renewed thinking about decolonisation

Prof Steyn said: “We can develop our vocabulary to understand our real differences.” She noted that we are all part of reproducing, resisting and reframing the current order.

Universities should be a place where questions can be asked, Prof Ramugondo said. She elaborated on the term decolonisation, saying we needed to investigate how we related and reflected on it, mentioning the myths that surrounded the term. “We should renew our thinking [about decolonisation] at universities,” she said.

“We can develop our vocabulary
to understand our real differences.”

What does a transformed UFS look like?
According to Luwaca unity isn’t something that can be faked, but everybody should work towards it, building a rainbow nation together. It is important for everyone to be on the same page: “We have to ask ourselves what a transformed university looks like.”

Prof Petersen said it was important to often pause and reflect: “Reflection should stimulate action. Reflection is not something without action.”

After the discussion, a lively question-and-answer session with the panellists took place. Prof André Keet, director of the IRSJ and facilitator of the discussion, suggested the gathering should be the start of many similar engagements.

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