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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Van Niekerk shines in Ostrava and breaks 300 m world record
2017-06-29

Description: Van Niekerk shines in Ostrava  Tags: Van Niekerk shines in Ostrava

Wayde van Niekerk is in great form leading up to the
World Championships in London in August.
Photo: Khothatso Mokone

Usain Bolt believes Wayde van Niekerk could well be his successor. Bolt, who has won eight Olympic and 11 world gold medals in his career, doesn’t doubt that the Kovsie athlete could take over the reins as an athletic superstar.

This after Van Niekerk broke another world record by Michael Johnson – 30.85 seconds in the 300 m which Johnson set in Pretoria in 2000 – at the IAAF Golden Spike meeting in Ostrava, Czech Republic, on 28 June 2017. He took the honours in the 300 m in a time of 30.81 seconds. In 2016, Van Niekerk also improved on Johnson’s 400 m world record (43.18 s) with a time of 43.03 s at the Rio Olympics.

Unique honour over four distances
Because the 300 m event is not run very often, the record will be regarded as the world’s best by the IAAF. According to the IAAF, the 24-year-old Van Niekerk is now also the first man to run a sub-10 for the 100 m, sub-20 for 200 m, sub-31 for 300 m, and sub-44 for 400 m.

The legendary Bolt, who is in his final season, admitted that Van Niekerk could take over from him. “I think he really wants to be a sprinter, because he's set a personal best in the 100 m this year,” he said to AFP.

“He's shown that he's ready for the challenge. He's really down to earth, he's really humble, he's a great person. He listens and wants to be good, and if he continues like this he'll take over track and field."

Great run prior to Czech Republic
The 300 m world record follows after Van Niekerk also ran a personal best time of 9.94 in the 100 m in Velenje, Slovenia, on 20 June 2017. The 400 m world record-holder also became the South African record-holder in the 200 m again when ran a 19.84 in the 200 m at the Racers Grand Prix in Kingston, Jamaica, on 11 June 2017.

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