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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Moffett’s third book provides comprehensive guide to Basotho medicinal plants
2017-07-26

 Description: Prof Moffett’s book  Tags: Prof Moffett’s book  

Prof Rodney Moffett’s three books documenting Basotho
plants, animals, and the history of the Free State and Lesotho.
Photo: Thabo Kessah


Prof Rodney Moffett has recently published his third book, Basotho Medicinal Plants – Meriana ya Dimela Tsa Basotho. This latest offering deals only with medicinal uses and is based on the data from his first book, Sesotho Plant and Animal Names and Plants Used by the Basotho.

“The latest book came about after a Sesotho language advisor in the Free State Department of Education suggested that there was a need for the medicinal uses of plants by the Basotho to be documented in the vernacular. In a situation where there is an almost total lack of scientific literature in the vernacular, the greatest value of this book therefore, is that it provides a comprehensive guide to the medicinal uses of plants in Sesotho,” said Prof Moffett, Honorary Research Associate in the Department of Plant Sciences on the Qwaqwa Campus.

Book lists names of plants in Sesotho
“It comprises two parts. Part one lists the medicinal categories and plants used, and part two lists the medicinal uses arranged according to the Sesotho names of the plants. It is easy to read, as the information is presented alphabetically with the Sesotho name first, followed by the scientific name and usage thereof. Because a plant often has more than one Sesotho name, the scientific name is included to identify it.”

Prof Chris Nhlapo, Deputy Vice-Chancellor of the Cape Peninsula University of Technology, and Prof Ntsamaeeng Moteetee from the University of Johannesburg are impressed with the book, respectively saying that it assists in documenting the deep indigenous knowledge of the “proud tradition of the Basotho Nation” and it is “an important contribution to the documentation of medicinal plant uses”.

The title of Prof Moffet’s second book was A Biographical Dictionary of Contributors to the Natural History of the Free State and Lesotho.

Prof Moffett was honoured with a Lifetime Researcher Award during the Academic and Research Awards on the Qwaqwa Campus in November.

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