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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

OSM Camerata first place winner in international competition
2017-09-08

Description: Camerata Tags: OSM Camerata, Ictus International Music Competition, Marius Coetzee, Odeion School of Music 

The OSM Camerata with conductors, Xavier Cloete and
Gerhard de Jager received first place in the
University/Conservatory Orchestra category.
Photo: Supplied



The OSM Camerata received first place in the 2017 Ictus International Music Competition for bands and orchestras. Marius Coetzee from the Odeion School of Music at the University of the Free State said: “The award was announced in time for the celebration of the orchestra’s fifth birthday.”

OSM a catalyst for excellence
The OSMC was strategically founded in 2012 by Coetzee as the OSM’s flagship chamber ensemble, with the main objective of creating a catalyst for excellence.

Over the past five years, the OSMC has premiered 15 new works by South African composers specially commissioned for them. Highlights remain its participation in the 13th International Conservatory Festival in St Petersburg Russia, where the ensemble received a standing ovation during a gala concert in the Glazunov Concert Hall, as well as the world première of the Cello Concerto for an African Cellist by South African composer, Hans Huyssen, with South African cellist, Heleen du Plessis as soloist. The CD was released in 2014 on the New Zealand Classical Music label, Ode Records in Auckland, New Zealand and was one of five CDs nominated for the Listeners' Choice Award New York in March 2014.

Competition draws participation from Washington to Bloemfontein
The inaugural year of this annual competition drew applicants from Washington State in the US all the way to Bloemfontein in the Free State. Video submissions were judged and narrowed down to a final round from which prize winners were selected.

The OSM Camerata with conductors, Xavier Cloete and Gerhard De Jager, received first place in the University/Conservatory Orchestra category. 

The competition was founded to highlight the work that music educators, conductors, students, performers and community members make in ensembles at the university, community, youth, high school and middle school levels. 

Competition director, Alex Serio says that “many people do not realise the amount of work that it takes to make these ensembles run. What is more is that most of the public does not realise the level of artistic excellence that can be achieved in these ensembles. Ictus International Music Competition was founded to highlight this level

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