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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Compassion improves psychological well-being and reduces emotional distress
2017-09-27

Description: TEDxUFS   Tags: TEDxUFS

Participants in the Kindness Project sharing a
Random Act of Kindness with the cleaning staff,
Mathabiso Sehlabaka and Madineo Mokoena.
Photo: Thabo Kessah

Various studies have reported that the cultivation and practice of compassion may result in improved self-esteem, a decrease in depression and anxiety, increase in subjective well-being, and overall improvement in physical and psychological health. This is according to Counselling Psychologist, Tobias van den Bergh, during the Kindness Project (KP) on the Qwaqwa Campus.

“Students that are involved in this project have shown statistically significant improvements in overall well-being and compassion towards themselves and others,” said Van den Bergh, the project leader and Head of Department: Student Counselling and Development, Qwaqwa Campus.

“In addition, student participants of the compassion-based intervention showed a decrease in their experience of debilitating emotions and depressive symptoms, as well as a significant increase in measurements of positive affect (an indication of life vitality), self-compassion, and well-being. Humans appear to be genetically programmed to be kind. Studies have shown that the same brain structures that are activated when we procreate (i.e. have sex) or eat chocolates, are activated when we are kind. Thus, it means showing an instinctive predisposition towards compassion for our kin and others. Kindness also appears to be contagious. Whenever we observe kindness or experience kindness ourselves, we are much more likely to be compassionate towards our fellow human beings,” he said.

The KP is based on the Science of Compassion, with participants completing a four-week compassion-based intervention where they learned about and practised self-compassion and compassion towards others. In the last week of the programme, participants completed various Random Acts of Kindness off and on the campus.

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