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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Elinor Sisulu to present lecture at the UFS
2008-07-30

Human rights activist, Ms Elinor Sisulu, will deliver a Women’s Day lecture, titled: “Voiceless and voteless, fleeing zanuphobia into xenophobia: A Zimbabwean woman’s perspective of National Women’s Day” at the University of the Free State in Bloemfontein on Wednesday next week.
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She was invited by the Faculty of the Humanities at the UFS to deliver the lecture on Wednesday 6 August because of her stature as an activist and writer and her views on the topical issue of Zimbabwe.

The Vice-Dean of the Faculty of the Humanities, Prof Engela Pretorius, said the UFS was keen to engage the larger community on these kinds of issues and invites all interested people to attend.

Ms Sisulu is a writer, human rights activist and political analyst. Born in Zimbabwe, she was educated in Zimbabwe, Senegal and the Netherlands.

She combines training in history, English literature, development studies and feminist theory. In 1994 she published an award-winning children's book, “The Day Gogo Went to Vote”.

Her biography about her mother-in-law and father-in-law, titled “Walter and Albertina Sisulu: In Our Lifetime”, was published to critical acclaim in December 2002. The book was runner-up in the 2003 Alan Paton Non-fiction Award and won the 2003 Noma Award for publishing in Africa.

Ms Sisulu works in the South African office for the Crisis in Zimbabwe Coalition, the major umbrella body of Zimbabwean non-governmental organisations.

The lecture will start at 19:00 in the CR Swart Auditorium on the main campus in Bloemfontein.

Light refreshments will be served.

Those wishing to attend must please make a booking with Hettie Beukes at 051 401 2240 or beukeshs.hum@ufs.ac.za.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za  
30 July 2008
 

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