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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Delegates encouraged to ‘walk the talk’ on fraud prevention
2017-11-27

Description: Fraud Tags: fraud, corruption, crime, business, Free State, MEC of Finance, Elzabe Rockman, PricewaterhouseCoopers, Standard Bank, Association of Certified Fraud Examiners, Monte Bello 

Representatives from the UFS Business School with Nick Olivier, Certified
Fraud Examiner (right), at the International Fraud Awareness Week’s
Free State Conference.
Photo: Lerato Sebe


‘Walking the Talk on Fraud Prevention’ was this year’s theme during the annual International Fraud Awareness Week’s Free State Conference held at Monte Bello, Bloemfontein, on 16 and 17 November.

The conference was hosted by the Business School of the University of the Free State (UFS), in collaboration with the Free State Provincial Treasury, Standard Bank, the Association of Certified Fraud Examiners (ACFE), and PricewaterhouseCoopers.

Detecting and taking action against corruption
The Free State MEC of Finance, Honourable Elzabe Rockman, says corruption is not only a provincial or national issue, but rather a global issue. “Through this interaction with the International Fraud Awareness Week, we reach a much broader audience, both inside and outside government.” She says this should make a direct contribution to increasing awareness of what constitutes fraud, and improving our ability to detect it and to take action.

Implications caused by fraud
One of the speakers at the seminar, Nick Olivier, a Certified Fraud Examiner (CFE), did a presentation labelled, ‘WTF – Where to focus in the corruption noise’, highlighting the impact which fraudulent crime has on companies. “With the private sector, the impact is huge because the company will have to spend money on investigations or lawyers to get their money back.” He mentions that in government, various things are affected by fraud, such as the economy, the country’s resources, the lives of citizens and the society. 
“We need to start obeying the regulations which were implemented in our environments so that we do not need to do investigations, because every citizen has a duty to do the right thing,” says Olivier.

Tender procurement and bribery were listed as the top corruption crimes in both the private and government sectors.

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