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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Distinguished academic bids farewell to UFS
2008-09-05

 
Prof Nel and his wife, Olivia

The Director of the Centre for Africa Studies (CAS) at the University of the Free State (UFS), Prof Phillip Nel, is leaving the University after 33 years of service.

Prof Nel has decided to scale down his involvement with the UFS and CAS to spend more time with his wife, Olivia, and his family and doing more research.

“There comes a time that one must go and this is it for me, but from time to time I wonder whether I have done all that I was meant to do”, said Prof Nel. “I strongly believe that no one is irreplaceable and I know that the Centre for Africa Studies is in good hands.”

His successor, Prof Anwar Osman, an internationally renowned academic himself, assumed the directorship of CAS on 1 September 2008.

“My intention is to build on the groundwork done thus far and to broaden the teaching and research base of the Centre to include the natural sciences as well, truly making CAS a beacon for multidisciplinary study”, said Prof Osman.

“The future success of this centre will be a lasting testament to Prof Nel’s visionary leadership.”

Although he will be leaving the ranks of the full-time employed at the UFS, Prof Nel will still be involved with CAS’s research programme and still has a number of active research projects, such as the SANPAD Project, entitled Communities in Communion, which involves the dynamics of sacred sites and individual and community cultural and spiritual identity construction.

He launched CAS in 2007 to promote a stronger focus on African issues in all activities at the UFS and to fulfil an academic role by linking the realities of Africa to education, research and community service programmes.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za
4 September 2008
 

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