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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Health Sciences dean’s term extended
2008-09-17

The Council of the University of the Free State (UFS) has unanimously decided to extend the term of office of the Dean of the Faculty of Health Sciences, Prof Letticia Moja, by another five years.

Prof Moja became the first black woman to be appointed dean of a medical faculty in South Africa in 2003.

She has been at the helm of the Faculty of Health Sciences at the UFS for the past six years, first as the Acting Dean and then as the Dean. Under her leadership the faculty has achieved great successes and remains one of the leading Health Sciences faculties in South Africa.

However, she still faces many challenges that she hopes to overcome in the next five years to fully accomplish the mission of the faculty to promote the well-being of the community by means of education, research, community service and comprehensive health care delivery.

She hopes to achieve this by attracting and retaining dedicated and well-qualified staff to the faculty, supporting students in all aspects of their life, implementing regular assessment of the teaching and learning environment, mentoring young researchers and increasing the intake of students from previously disadvantaged communities.

Prof Moja is the current vice-president of the Health Professions Council of South Africa and the treasurer of the central region of the South African Association of Health Educationalists.

She is also the director of the UFS’s Grow Our Own Timber project which is aimed at developing black academics. She is a member of the Medical and Dental Council and also serves on its executive committee.

Her current term of office expires on 30 November 2008.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za  
17 September 2008
 

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