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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

USSA cross country 2008
2008-10-16

The student cross country championships of 2008 took place on the 29 and 30 September 2008 at the University of Kwazulu Natal.

‘n Total of 109 athletes took part. The Kovsies men`s team was Boy Soke, Johan Cronje, Michael Tlhoro, Dirk Gouws, Ben Smit and Antonie Peens. The womens team was represented by Este de Jager, Abongile Lerotholi, Thandi Malindi, Rone Reynecke en Maryna Swanepoel.

The women’s team took the honours by winning the team competition in the 4km race. They finished as follows: De Jager 3rd, Lerotholi 5th, Malindi 6th, Reynecke 7th and Swanepoel 16th.

The men’s team also did well under circumstances – Our number 2 and 3 runners were injured and Antonie Peens, our number 5, was diagnosed with measles on the morning of the race. They finished 3rd in the men`s 4km race. However the men can kept their heads high. They finished as follow: Soke 2nd, Cronje 12th, Tlhoro 17th, Gouws 29th and Smit 39 th.

In the road relay race our womens team again did us proud by winning the race by a huge margin. Our team was Thandi Malindi, Abongile Lerotholi and Este de Jager.

The men`s team perform well under difficult circumstances by finishing 4th.  The team was Dirk Gouws, Johan Cronje, Michael Tlhoro en Boy Soke.

Este de Jager

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