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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

First book on Bloemfontein published in 25 years
2008-10-21

 

During the launch of the book "Spatialities of Urban Change" are, from the left, front: Mr Malefetsane Mokoena, General Manager: Housing at the Mangaung Local Municipality and one of the co-authors of the book, Mr Amos Goliath, Executive Director: Corporate Affairs at the Mangaung Local Municipality, Ms Rothea van Biljon, Chairperson of the Afrikaanse Handelsinstituut Bloemfontein; back: Prof. Lochner Marais, editor of the book from the Centre for Development Support at the UFS, and Prof. Gustav Visser, editor of the book from the Department of Geography at the UFS. Photo Stephen Collett

 The University of the Free State (UFS) has published a book on Bloemfontein for the first time in 25 years. The book, titled “Spatialities of Urban Change”, is the first South African scholarly account in book form of spatial themes on urban change in a secondary city in South Africa. The book was recently launched on the Main Campus in Bloemfontein.

The editors of the book are Prof. Lochner Marais from the Centre for Development Support and Prof. Gustav Visser from the Department of Geography, both from the UFS. Their co-authors are five Ph.D. students in Development Studies, one Ph.D. student in Geography and one master’s student in Development Studies.

According to Prof. Visser, there is a gap in the market for new perspectives on how cities work and how urban theory can develop. This book will contribute to filling that gap. The book also manages to involve students and their research – giving them the opportunity to have their research published.

The book addresses various aspects of Bloemfontein’s spatiality and issues such as suburbanization and the subsequent decline of the central business district, the city’s tourism potential and the impact of the Volksblad Arts Festival on re-imaging the city as a place that has something to offer any visitor, are discussed among others. Other topics include the suburb Westdene and how diverse spatiality manifests itself at this scale, and white flight from the inner city areas.

“A central theme running through the book is how the urban discourse of Bloemfontein relate to the country’s metropolitan core and conversely to other secondary cities,“ says Prof. Visser.

Media Release:
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
22 October 2008

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