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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Outgoing Rector donates computer to security guard
2008-10-23

 
Prof. Frederick Fourie and Mr Teli Mohlakoana
Photo: Mangaliso Radebe
The outgoing Rector and Vice-Chancellor of the University of the Free State (UFS), Prof. Frederick Fourie, has donated a laptop computer to a security guard at the UFS to enable him to continue writing radio dramas.

Mr Teli Mohlakoana was one of the security guards dispatched to Prof. Fourie’s house at the time of the Reitz video incident.

Prof. Fourie said it was during that time that he noticed Mr Mohlakoana busy writing, and approached him to find out what he was writing. He told Prof. Fourie he was writing his latest drama for Lesedi FM, something he has been doing for years without a computer.

Mr Mohlakoana started writing radio dramas in 1997, and is currently working on three dramas with 35 episodes each. His first drama, “Na Ke Phoso” (Am I Wrong?) was aired in 2004. He said the laptop will make his job much easier.

“I am very happy to have received this gift, and I intend to use it to teach other people to write dramas”, he said.

Mr Mohlakoana is also busy writing a book titled “Dikapeso” (Graduations), as well as a stage play, with the assistance of the Drama Department. He started working for the UFS in 2006.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za  
22 October 2008
 

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