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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Odeion: The Fortepiano in the late 18 th century - A lecture recital by John Reid Coulter, Monday, 27 October 2008
2008-10-01

The Fortepiano in the late 18 th century - A lecture recital by John Reid Coulter
Monday, 27 October 2008
Odeion
19:30


with
Deirdré Blignaut ~ soprano
Carmi Nel ~ violin
Piet van Rooyen ~ violoncello
Nicol Viljoen ~ fortepiano

including songs & solos by
W.A. Mozart, F.J. Haydn, C.P.E. Bach
& four Scottish & Irish folk song arrangements
by L. van Beethoven

John Reid Coulter is one South Africa’s leading exponents of historical performance practice. He completed his studies in harpsichord with Jacques Ogg at the Royal Conservatory in The Hague. He has taught at the universities of Potchefstroom, Witwatersrand and Pretoria. John has an avid interest in the building of early keyboard instruments and has built a number of harpsichords and a fortepiano. He has performed as soloist and continuo player in The Netherlands, Norway and Germany. His baroque ensemble ‘Banda di Giovanni’ has premiered a number of works in South Africa, the most recent being the cantata ‘Apollo e Dafne’ by G.F. Handel in 2004 and the Serenata à tre ‘Mio cor, povero cor’ by Antonio Vivaldi in May 2007. John is also well known as an adjudicator at music festivals and as a composer has won numerous awards.

Deirdré Blignaut obtained a BA (Languages) degree from the University of the North West in 1988. She graduated cum laude and was awarded Best Student, Faculty of Arts. She began her career as translator at Transnet and later joined the Department of Arts and Culture as terminologist. In 1995 music become her full-time career and field of study. She studied singing with Prof Werner Nel until 2000 and repertoire with the late Anna Bender currently she studies with Eugenie Chopin. In 2002 she obtained a Performer’s Licentiate cum laude and was invited to participate in the Unisa International Bursary Competition. Deirdre is currently she is working towards a MMus (Performing Arts) through the University of Pretoria. She teaches voice at Pro Arte Alphen Park, lectures Methodology of Singing at the University of Pretoria and was recently appointed voice lecturer at the School of Music, North West University.

The fortepiano used in the concert was built by John Reid Coulter in 1986 and is a copy of a Stein fortepiano ca. 1780.

Admission: Free

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