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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Research development develops young researchers
2008-11-19
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| Researchers who attended the workshop are, from the left, front: Ms Florence Tladi, Department of Psychology, Ms Makoena Moloi, Department of Plant Sciences, Ms Tobeka Mehlomakhulu, Department of Geography, Ms Nomampondomise Molefe, Department of Chemistry, Dr Micheal van Wyk, Department of Curriculum Studies, Prof. Mabokang ‘Monnapula-Mapesela, CHESD; back: Dr Sebolai, Prof. Muriel Meiring, Department of Hematology and Cell Biology, Mr Mathabatha Maleka, Department of Genetics, Mr Coleman, Dr Gregory Alexander, Department of Psychology of Education, Ms Dorine Masiangoako, Department of Chemistry, and Ms Moipone Mokoena, Department of Chemistry. |
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Dr Olihile Sebolai, Directorate Research Development, recently organised a series of workshops which is aimed at imparting new skills and knowledge to young and emerging academics.
The directorate endeavored to capacitate the new generation of researchers at the university with skills enable them to be established within the competitive mainstream of research. This is in line with the research strategy of the university that seeks to cultivate a strong culture of research.
Amongst others the workshops focused on innovative ways of adding value to student supervision and improving research project management skills. These workshops were facilitated by Dr Pieter du Toit from the University of Pretoria and Mr William Coleman from the Central University of Technology. Follow up sessions are planned for 2009 to assess the impact of these workshops. |