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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Marjolein Sêr Group to compete in America
2009-04-03

 
Prof. Ezekiel Moraka, Vice-Rector: Student Affairs at the UFS and the Sêr Group of Majolein residence.
Photo: Hannes Pieterse
A group of 17 female students from the University of the Free State’s (UFS) Marjolein Hostel have been selected to represent the university in an international a capella singing competition in New York, USA on 18 April 2009.

It is the first time that a South African singing group will take part in this competition.

The group has been singing together with coach Ms Marisan Nienkemper since 2006. In that year they obtained a second place and in 2008 they won the UFS’s serenade competition as well as received the prize for the best newly-composed a capella song. They also competed in the national university serenade competition in August 2008.

Ms Nienkemper contacted Ms Amanda Newman, the executive director of Varsity Vocals in the USA at the end of last year. Based on a video audition, she invited the group to compete in the international competition. She also regarded the group as having a high standard.

“We are extremely proud of Marjolein. Student life is an important part of higher education institutions and of the total development of students. The fact that one of our residences qualified for this competition is an indication of the vibrancy of our student life,” said Prof. Ezekiel Moraka, Vice-Rector: Student Affairs of the UFS.

The group will be leaving South Africa on 11 April 2009. The competition will take place at the Lincoln Center for the Performing Arts.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
2 April 2009

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