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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsie-Alumni Trust provides financial support to gifted young persons
2009-07-08

 
Kovsie-Alumni Trust of the University of the Free State (UFS) provides financial support to gifted young persons. This year, the Trust has already granted R24 000 to students with disabilities and R28 500 to ad hoc applications for financial support. Amongst others, financial support of R224 888 was given to students from the Alumni Donation Funds. The contributions of generous donators to the Trust Fund are used to award academic, cultural and sport bursaries to deserving prospective as well as current Kovsie students. Here are, from the left: PK Nkate, a blind honours student in Business Management, who received R6 000 from the Trust, Ralph de Kramer, who received R3 500 for his ad hoc application; back: Adv Seef Hefer, Chairperson of the Trust, Ms Francis Hoexter, member of the Trust, Leendert Kramer, who received R60000 for his ad hoc application and Mr Ryno Opperman, member of the Trust. Other bursaries were awarded to Eleanor Bernard and Nandi Venter, Master’s students from the Department of Afrikaans and Dutch, French and German, who each received half of the NNP bursaries with the total value of R20 000 and Magteld Smith, a blind Ph.D. student in BA to whom the Sapcor Bursary was awarded. Carien Gordon, Geoff Bezuidenhout and Ilana van der Merwe received R6 000, R3 500 and R3 500 respectively, according to their ad hoc applications.
Photo: Dries Myburgh

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