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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

The best black and white learners must come and study here
2009-09-17

 
At the meeting, arranged by the Faculty of Economic and Management Sciences, were from the left: Mr Tshdiso Makoelle, Clocolan High School; Mr Braam van Wyk, St Michael's School in Bloemfontein; Prof. Jonathan Jansen, Rector and Vice-Chancellor of the University of the Free State (UFS); Mr Izak Coetzee, Dr Blok Secondary School in Bloemfontein and Mr Okkie Botha, Witteberg High School in Bethlehem.
Photo: Stephen Collett
 “I want to make this university one of the best universities in the country and in the world. For this I will need the support of principals and teachers.” These were the words of Prof. Jonathan Jansen, Rector and Vice-Chancellor of the University of the Free State (UFS) during a recent meeting with school principals held on the Main Campus in Bloemfontein, which was arranged by the Faculty of Economic and Management Sciences.

“I want the best black and white learners to come and study here and therefore I am going to visit schools in the region to find out how we can attract the best learners,” he said.
The most important influence on learners is their teachers and principal. “This why I need the support of teachers and principals to guide their learners to come and study here,” said Prof. Jansen.

Prof. Jansen said that it was of no use to work with Grade 11 and 12 learners only as it was mostly too late to change their minds. He wants to work with Grade 10 learners and make them excited about university life so that they will know what the UFS can offer them. He will also visit poor and rural schools and tell them about the UFS.

“When a Kovsie graduate walks down the street something must distinguish him/her from other graduates. Our graduates must be able to work anywhere in the world,” he said.

“Students must have the ability to live with other people and to be comfortable around people who look and speak differently than them. I want our students to be multi-lingual and to be comfortable around other students and people in terms of religion, race, language, etc. Students who do not have this added value will not be successful in the market,” he said.

Media Release
Issued by: Lacea Loader
Deputy Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
16 September 2009

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