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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof. Hennie Snyman named national agriculturist of the year
2009-11-18

Here is Prof. Snyman (right) with Adv. Koos Nel, Marketing Manager of Old Mutual, one of the sponsors.
Photo: Ben Rootman

This past weekend Prof. Hennie Snyman from the Department of Animal, Wildlife and Grassland Sciences at the University of the Free State (UFS) became the second agriculturist in a row at the UFS that was named the national agriculturist of the year by Agricultural Writers SA. This honour was bestowed upon Prof. Maryke Labuschagne from the Department of Plant Sciences at the UFS last year. Prof. Snyman is, amongst others, honoured because he is one of the few South African agriculturists that are making a comprehensive contribution towards the Grasslands and Agricultural Sciences.

His broad field of research over the past 32 years has been the sustainable utilisation of the grasslands ecosystem in drier areas in particular. Various other grasslands projects in various fields have also been undertaken by him. The adjudication took place in five categories, namely the contribution towards agriculture in general, the contribution towards the development of the farmer, adaptation to changing circumstances in the agricultural industry, national and international recognition in the agricultural industry and the field in which he is an expert and achievements already attained. Prof. Snyman received the award during a dinner of the Agricultural Writers SA in Pretoria.

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