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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
UFS awards its innovative thinkers
2009-11-18
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Here are, from the left: Prof. Van Wyk with first-prize winners Precious Setlaba and Themba Motsoeneng and Prof. Muriel Meiring, the students’ promoter.
Photo: Stephen Collett |
The University of the Free State (UFS) recently announced the winners of the Innovation Fund Competition. This national competition, which is organised by the Department of Science and Technology aims to promote entrepreneurship through the commercialisation of the innovative ideas of young entrepreneurs.
Every participating educational institution first has an in-house competition in which a total prize money of R100 000 is at stake. At the UFS 14 business plans from students were received and evaluated by six external adjudicators. The three winners now have to take part in Phase II of the competition where 60 competitors from 20 universities will compete. The winners of the National Competition will receive prizes of up to R300 000. This money must be used for the development of the innovative idea with which the prize was won.
The first prize in the UFS’s Innovation Fund Competition of R50 000 was won by Themba Motsoeneng and Precious Setlaba from the Department of Haematology for the development of low-cost diagnostic assays for thrombotic diseases and bleeding disorders with the aim of supplying these test assays at a much lower cost to pathology laboratories all over the country. “This exciting idea appealed to many of the judges, especially because it can contribute to low cost health care in the country,” says Prof. Gerrit van Wyk, organiser of the Innovation Fund Competition at the UFS. The second prize of R30 000 was won by Charl Jaftha, MSc student in Physics. He has developed a low-cost hearing aid the size of a cigarette box. It contains a microphone and electronics to amplify the sound. The third prize of R20 000 was won by Adriaan Taylor and Jaco Brink, both MBA students. They designed a two-in-one lawnmower that would enable the average gardener with a bulky garden to shred the garden refuse and recycle it through composting or disposal through the normal disposal system. “One judge called this a novel use of existing technology,” says Prof. Van Wyk.