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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

A Strategic Maths and Science Education Initiative at the Qwaqwa Campus
2009-11-17

Representatives of the Natural and Agricultural Sciences and Education Faculties as well as the Qwaqwa Campus Management recently convened a workshop on a strategic new Maths and Science Education Initiative to be offered from the Qwaqwa Campus of the University of the Free State (UFS). The two faculties have agreed to partner in order to offer programmes that will contribute to the development of well-qualified Maths and Science teachers and the improvement of Maths and Science education in local schools.

The programme will be based on a strong research foundation and will also involve extensive partnerships with schools in the Qwaqwa region. Amongst others, the initiative will include the possible introduction of a new programme specifically targeting prospective Maths and Science teachers, as well as the development of modules that focus on the critical content that needs to be covered in the curriculum at Grades 10 to 12.

The initiative emerges against a background of major shortages in science and technology skills in the country, poor performance in Maths and Science in South African schools, a lack of resources such as laboratories in schools, concerns about the content knowledge of qualified teachers and the high demand for Maths and Science teachers, together with very small numbers actually qualifying in these areas. A committee with representatives from both faculties as well as representatives from the Qwaqwa and Main Campuses has been formed to take the planning for this initiative forward. A full business plan is due to be completed in early 2010.

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