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Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS's international advisory board holds first meeting
2009-11-28

Members of the International Advisory Board of the UFS in discussion with Prof. Dennis Francis (right), who is appointed as Dean of the Faculty of Education from the beginning of 2010. With him are Prof. Alice Pell from Cornell University in the USA and Dr Uri Ofir from Evalnet in Switzerland.
Photo:  Leatitia Pienaar


The International Advisory Board of the University of the Free State (UFS) had its first meeting on the Main Campus in Bloemfontein this week. It coincided with the launch of the six research clusters of the UFS.

Prof. Aldo Stroebel, Director: Internationalisation at the UFS, says internationalisation is a strategic priority to reach the University’s strategic goals. Internationalisation will bring a global awareness at all levels and will serve as a co-shaping factor and an instrument to produce well-rounded, internationally competent staff and students. It will also be an instrument to promote diversity, advance the UFS’s international standing and initiate and promote international collaborative research.

The advisory board will advise and guide the UFS leadership in the internationalisation process. He said the board would provide strategic guidance to the internationalisation efforts of the UFS and bring cutting-edge expertise to bear on the internationalisation policies, strategies and action plans of the institution.

Its members will help ensure that the University leadership is aware of relevant international trends and opportunities, and the board will use their experience to advise on appropriate actions. They will also act as advocates for the University in their own spheres of influence.

The board consists of Dr Jane Knight of the Ontario Institute for Studies in Education, University of Toronto, Canada; Prof. Alice Pell of the Cornell University, USA; Prof. Masafumi Nagao of the International Christian University, Japan; Dr Khotso Mokhele of Impala Platinum Holdings, South Africa; Prof. Joseph Stetar of the Seton Hall University, USA; and Dr Uri Ofir of Evalnet, Switzerland. Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS, is the Chairperson of the board.

Prof. Stroebel says the UFS is honoured to have people of international standing and who are highly regarded in various fields on the board to guide the institution in its internationalisation endeavours.

Media release
Issued by: Lacea Loader
Deputy Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
27 November 2009
 

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