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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

World-renowned researcher and author facilitates at Kovsies
2010-03-08

 
The facilitator with three academics of the Faculty of Education: (from the left) Emmie van Wyk (CHESD), Jean McNiff, Annette Wilkinson (CHESD), and Adri Beylefeld (Office of the Dean).
Jean McNiff, world-renowned action researcher and author of 19 published books, created a buzz on the University of the Free State Campus last week.

She spent 23 February at the Faculty of Education. The day started off with a panel discussion between six senior staff members of the faculty and of the UFS Planning Unit. Thereafter 24 academic staff members attended a seminar where they were introduced to the methodology and conventions of action research (AR).

The full-day workshop on 24 February was attended by 30 UFS and 30 CUT staff members. The workshop – with the interesting title, Using our educational responsibilities to transform our violent histories into life-affirming futures – was participative and interactive, true to the nature of AR.

In addition to the 84 staff members who have already benefitted from these sessions, 12 staff members from the QwaQwa Campus will have the opportunity to watch the video-taped version of the workshop.

Jean McNiff's book Action research for professional development is available as a free download on her webpage www.jeanmcniff.com .

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