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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Faculty of Theology appoints scholar from Yale University
2010-03-11

 
Prof. Adriaan Neele
Photo: Stephen Collett


Prof. Adriaan Neel from Yale University in New Haven in the United States of America recently delivered his inaugural lecture as Professor Extraordinary in the Department of Ecclesiology at the University of the Free State (UFS). His inaugural lecture coincided with the official opening of the Jonathan Edwards Center Africa in the Faculty of Theology of the UFS.

The appointment of Prof. Neele as Professor Extraordinary in the Department of Ecclesiology follows the vast growth of the Jonathan Edwards Centre Africa.

Prof. Neele delivered his inaugural address on: A Transitional Moment in Theology where he argued for the classicality and catholicity of Edwards’ theology.

In his lecture Prof. Neele concluded: “In the midst of the challenging and changing times of 1737-42 of New England’s history and theology, Edwards revisited fundamental questions of theological prolegomena. The formulation of his answers demonstrated not only continuity and discontinuity but also a demanding appropriation of intellectual thought, that of the catholicity and classicality of theology. The discourse was drafted and heard in Northampton, published in 1788, and soon afterwards forgotten; yet its message was timeless, ‘Practice according to what knowledge you have. This will be the way to know more’.

“The appointment at this prestige university of Southern Africa is both an honour and humbling. I look forward to a beneficial and academic engagement with students, as well as to serve the academy and the church,” Prof. Neele said.

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