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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Service Learning workshop at the Qwaqwa Campus
2010-03-11

 
At the workshop were, from the left: Dr Luzelle Naudé (Senior Lecturer: Department of Psychology), Prof. Mabel Erasmus (Head: Service Learning Division), Ms Moodi Matsoso (Coordinator Community Services – Qwaqwa Campus) and Dr Elize Smuts (Staff Development Facilitator).
Photo: Dikgapane Makhetha


The Service Learning Division at the University of the Free State (UFS) recently held a staff enrichment session in the Senate Hall on the Qwaqwa Campus of the UFS. Staff members who are involved in Service Learning, or interested to learn more about it had an opportunity to share their experiences and ideas. The workshop presented an opportunity for the discovery of an academic niche through participants who demonstrated fervour in the initiation and development of more new Service Learning modules. The introduction of two separate skills enhancement programmes, HES717 and HES/FES522 endorsed prospects of a successful future for Service Learning and Community Engagement at the Qwaqwa Campus.

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