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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

World renowned cardiothoracic surgeons convene at UFS
2010-03-14

World-renowned cardiothoracic surgeons from around the world will be the guests of the Department of Cardiothoracic Surgery at the University of the Free State (UFS) when a workshop for cardiothoracic surgeons is presented at the UFS Faculty of Health from Monday, 15 March to Wednesday, 17 March 2010.

The workshop is presented by the European Association of Cardiothoracic Surgery (EACTS), which focuses on development and training in Africa.

Prof. Francis Smit, Head of the UFS Department of Cardiothoracic Surgery and also member of the international cooperation committee of EACTS, says EACTS have selected the UFS, and specifically Bloemfontein, to be the site for their African Training and Education outreach. “We are extremely honoured by this after working at it for more than four years.”

Seven world-renowned cardiothoracic surgeons, including three former presidents of EACTS, will present the training courses in Bloemfontein from 15-17 March 2010. These surgeons are from the United States of America, Norway, the Netherlands, Belgium, Switzerland and Scotland.

The European Cardiovascular Technologists are sending a perfusionist as well to present a perfusion workshop on Wednesday, 17 March 2010. The last day will be devoted to advanced surgical techniques.

The programme consists of a two-day scientific course that addresses research issues. All the invited speakers are well-known and established researchers. They all have been editors/editorial staff members of major international journals.

Prof. Smit says, “The knowledge transfer to South African surgeons can be phenomenal. Young and established surgeons can also meet the experts and improve their skills in conducting and successfully publish results.”

More than a hundred participants are expected for the workshops of the first two days, of which forty from abroad. The last day would be open registration and more than 150 people are expected.

Prof. Smit says, “This is a wonderful opportunity for us to educate, stimulate and teach surgeons in South Africa. It will add to their knowledge base and introduce them to high quality research methodology that will certainly have an impact on our research output. Hopefully this will be a bi-annual event where we can teach our academic community at a very focused and high level supported by EACTS.”

Media release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
12 March 2010
 

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