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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Department of Architecture builds next generation of architects
2010-03-22

 
With Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS are René Malan en Sancha Olivier.


Since 1987 first-year architecture students have been building huts on campus annually as part of an introduction to architectural studies at the Department of Architecture at the University of the Free State (UFS).

According to Martie Bitzer, Senior Lecturer in the Department of Architecture, the students build these full-scale huts in groups of two, with responses to orientation, materials (grass, reads, earth construction – mud bricks), climate and community over a period of approximately three weeks.

On the day that the students completed their huts, Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS, visited the small community of 27 huts in the veld behind the Rag Farm. Here he was taken on a walk amongst the huts. He also addressed staff and students of the Department of Architecture

“I can smell excellence and goodness,” was some of Prof. Jansen’s remarks as he walked amongst the huts.

“Top students come to our Department of Architecture. Quality attracts quality. The recent achievements of this department are proof of this,” he said.

One of Kovsies final-year students, Wim Steenkamp, was named National Corobrik Architecture Student of the Year 2008. This was the second time in the past three years that a student from the UFS Department of Architecture has won this prestigious competition. The department also received unconditional accreditation from the South African Council for the Architecture Profession (SACAP) for all three courses offered, and over the past few years its students have won the Tripod Photography Competition, the National Cement and Concrete Institute Competition for honours students, and the Carl and Emily Fuchs Foundation Student Prestigious Prize.

This once again confirms the prestige the department enjoys in the field of architecture in South Africa. It is also proof of the quality of staff and the programmes offered at the department.
 

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