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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsies paint Bethlehem red!
2010-03-20

At the matric evening of the Secondary School Witteberg in Bethlehem were, from the left: Lebogang Motaung; Rozelle Venter; Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS; Ernest Bezuidenhout; Donald Motaung; and Mr Rudi Buys, Dean of Student Affairs at the UFS.
Photo: Lynda Greyling


“The learners of the High School Witteberg are a wonderful example of the quality of students that we can expect as first years here at Kovsies next year,” Prof. Jonathan Jansen, Rector and Vice-Chancellor of the University of the Free State (UFS) said last night during a matric evening attended by 121 Grade 12 learners and their parents in a packed hall at the Secondary School Witteberg in Bethlehem.

Prof. Jansen and his wife Grace, as well as some of his colleagues were guests of honour at the event.

“We want to make a difference in the lives of our students at Kovsies and we want to ensure that our students make a difference in a divided world. This is why I want each Grade 12 learner who is here tonight to come and study at the UFS,” he told the learners and their parents.

“The UFS is going to become the university in the country that is serious about quality. We want to draw the best students. Quality entails hard work. It is about perseverance and your commitment towards your studies. That is the type of students we want.”

“My door is open to our students and they have access to come and talk to me. I also regularly sit at different places on the campus and then invite students to come and talk to me. I want our students to feel at home here.”

“I also want our students to feel free to talk about the use of language at the UFS. We love Afrikaans, English and Sesotho and are not going to fight about language. We are going to develop the use of Afrikaans so that more students can speak it – and this also goes for English and Sesotho.”

Prof. Jansen said that Kovsie students had to be balanced students. “Our students must also excel in sport, art, etc., because the development of students who are properly prepared for the workplace is what we strive for as a tertiary institution. Therefore we are going to establish an office that assists students in their career preparation and will offer students internships so that they can come into contact with leading firms in the commerce and industry sectors.”

“However, we shall also actively enhance our students’ learning experience and therefore we are going to send a group of first-year students overseas in the second semester this year to gain knowledge about issues like integration and collaboration.”

At the occasion Prof. Jansen announced that bursaries to study at the UFS in 2011 would be awarded to the two top Grade 12 learners of the school.

The Secondary School Witteberg had a 100% pass rate in the Grade 12 final examinations the past few years. In 2009 the school was seventh amongst the top 50 schools in the Free State Province. Five learners from the school were also amongst the top 20 learners in the Province last year. The school has already produced many top students for the UFS.

Mediaverklaring
Issued by: Lacea Loader
Director: Strategic Communication (acting)
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl@ufs.ac.za  
18 March 2010
 

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